Research Integrity

Notice on myostatin research

12 December 2015

NOTICE ON MYOSTATIN RESEARCH

As a top-ranked global university, Nanyang Technological University (NTU) upholds the highest research standards and international best practices in research. NTU has zero tolerance towards any form of research malpractice and will not hesitate to take action against anyone found to be lacking in research integrity.

In accordance with its policy of research integrity, NTU conducted an in-depth investigation following allegations of research malpractice.

This concerned research in myostatin that was jointly carried out by researchers from NTU, the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore (NUS). NTU took the lead in the investigation, after consulting with A*STAR and NUS.

The investigation found a number of instances of alterations to data. Consequently, NTU asked all the authors to assume responsibility by retracting the following papers. All authors have agreed, except for Sudarsanareddy Lokireddy. The authors and the papers are listed below:

The investigation also found other instances where data were presented without proper explanation of how they were derived. These however do not alter the scientific conclusions of the papers concerned. As a result, corrections and corrigenda have been requested for the following papers:

It has been agreed the following paper will be withdrawn at the behest of the journal editors:

Disciplinary procedures and further investigation are currently ongoing. We will not be making comments while this is ongoing but only after conclusions have been made at a later date.

Authors and their affiliations:

1 School of Biological Sciences, Nanyang Technological University

2 Singapore Institute for Clinical Sciences (A*STAR), Brenner Centre for Molecular Medicine

3 Department of Biochemistry, YLL School of Medicine, National University of Singapore