Academic Profile

Academic Profile

Assoc Prof Chew Sing Yian

Associate Professor, School of Chemical and Biomedical Engineering
Associate Professor, Lee Kong Chian School of Medicine

Assoc Prof Chew Sing Yian

Chew Sing Yian is currently in the School of Chemical & Biomedical Engineering, Division of Chemical & Biomolecular Engineering.
Research Interests
Biofunctional micro-/ nano-structured scaffolds for tissue engineering applications
Cellular responses to micro- /nano-structured scaffolds
Neural tissue engineering
Current Projects
  • Drug eluting dressings to promote diabetic wound healing
  • Establishing a scaffold-mediated approach for non-viral genome editing for regenerative medicine
  • Establishing a stroke model & regenerative treatment approach
  • Establishing neural cell membrane-coated particles for enhanced drug/gene delivery in the nervous system
  • Exploring New Treatment of Spinal Cord Injury by Synergising Regenerative Medicine and Rehabilitation
  • Gene-silencing Fibrous Scaffolds for Regenerative Medicine
  • High throughput label-free flow cytometry based on multiplex Raman spectroscopy
  • New Research Initiatives in Chemical and Bioengineering Areas
  • Producing electrospun fiber meshes from synthetic biodegradeable polymers
  • Radio frequency encoding ultrafast optical spectrometer and its demonstration in flow cytometry
  • Synthetic collagen peptide biomaterials for drug/gene delivery in nerve repair
  • The use of A Novel Wnt Inhibitor and Substrate Topography to Promote Healing in Transacted Nerve Injuries- Overcoming a Widespread and Debilitating Clinical Problem
Selected Publications
  • H Q Cao, K McHugh, S Y Chew and J M Anderson. (2010). The Topographical Effect of Electrospun Nanofibrous Scaffolds on the In Vivo and In Vitro Foreign Body Reaction. Journal of Biomedical Materials Research Part A, 93A(3), 1151-1159.
  • H Q Cao, L Ting and S Y Chew. (2009). The Application of Nanofibrous Scaffolds in Neural Tissue Engineering. Advanced Drug Delivery Reviews, 61(12), 1055-1064.
  • S Y Chew, R Mi, A Hoke, K W Leong. (2007). Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform. Advanced Functional Materials, 17, 1288-1296.
  • S Y Chew, R Mi, A Hoke, K W Leong. (2007). The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials, 29, 653?661.
  • S.Y. Chew, Y. Wen, Y. Dzenis and K.W. Leong. (2006). The Role of Electrospinning in the Emerging Field of Nanomedicine. Current Pharmaceutical Design, 12, 4751-4770.

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