|Academic Profile |
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Assoc Prof Ali Miserez
Associate Professor, School of Materials Science & Engineering
Associate Professor, School of Biological Sciences
|Ali Miserez is a Faculty member in the School of Materials Science and Engineering and the School of Biological Sciences at Nanyang Technological University (NTU) in Singapore. He graduated from the Ecole Polytechnique Fédérale de Lausanne (EPFL, Switzerland) with a PhD in Materials Science and Engineering (2003) and a specialization in advanced metal/ceramic composites and mechanics of materials. In 2004, he received a Swiss National Science Foundation post-doc fellowship and moved to the University of California, Santa Barbara (UCSB), where he was affiliated with the Materials Department and the Marine Science Institute. At UCSB, he expanded his research interest towards biological materials and biomimetics working in the group of Prof. Herb Waite. In 2009, he moved to NTU as an Assistant Professor, and in 2011 he was awarded the Singapore National Research Foundation (NRF) Fellowship, a $3 Million individual research grant for early career scientists.|
Dr. Miserez’s research is centered on revealing the molecular, physico-chemical, and structural principles from unique biological materials, and on translating these designs into novel biomimetic synthesis strategies. His research group is strongly cross-disciplinary, with molecular biologists, chemists, bio-physicists, and materials scientists combining their expertise towards bioinspired engineering from various angles, including protein biochemistry, extra-cellular tissue transcriptomic, polymer chemistry, biomimetic peptide design, biophysics, and nanomechanics. In recent years, his work has appeared in both general (Science, Nature Materials, Nature Biotechnology, Nature Chemical Biology, Advanced Materials) and specialized journals (Biomacromolecules, ACS Nano, JBC, Polymer Chemistry, etc, ). He has delivered numerous invited talks, including at various Gordon Research Conferences in the field of bioinspired materials and biomineralization.
|Structural properties of biological materials from the macro-scale to the nano-scale|
Multi-scale structural and mechanical properties of biological materials, including biominerals.
Elastomeric and structural properties of bioelastomers
Protein chemistry of sclerotized hard-tissues from marine organisms, such as Cephalopod
Single-molecular force spectroscopy of structural and elastic proteins
Underwater adhesion mechanisms of adhesive proteins
RNA-sequencing and proteomics of extra-cellular biological materials
Advanced Metal/Ceramic composites
Experimental Fracture Mechanics
- Bio-Inspired Materials: Lessons from Biopolymeric Tissues of Marine Organisms
- Bioactive Stem Cells Secretome-Enriched Hydrogels for Chronic Wound Healing
- Bioinspired Liquid Infused Coatings to Prevent Marine Biofouling in the Tropical Environment
- Biomimetic-Based Antifouling Coatings as a Route to Imporve Energy Efficiency of Ships and Port Structures
- Development of adhesive mimics for anti-fouling coatings and adhesion testing in the marine environment
- Frontiers in Physical and Life Sciences: Bio-inspired and Biomimetic Materials (NRF-NRFRF2011-06)
- Mechanisms of interactions in a model, synthetic biofilm community
- Membrane based Extraction for Lateral Flow Assaying of Contaminants in Water and Food Samples
- Modulation of Mesenchymal Stems Cells Differentiation using Biomimetic materials
- Molecular mechanisms of Barnacle Adhesion: A Combined Structural Biology and Computational Study
- Next-Gen Sequencing and Proteomics of Natural Biopolymers
- PREcipitation of Artificial Structural PROteins and POlySAccharides into nanocapsuLEs (PREPROPOSAL)
- PROJECT MIZU
- Phase Separation Regulated Life, In and Outside of Cells
- Potential Marine Antifouling Agents : Synthesis and Formulation of Novel Halogeneatd Cyclopent - 2 - ones
- Self-Assembly Mechanisms of 3D Protein-Based, Robust Marine Biopolymer
- S. Amini, S. Kolle, L. Petrone, O. Ahanotu, S. Sunny, C.N. Sutanto, S. Hoon, L. Cohen, J.C. Weaver, J. Aizenberg*, N. Vogel* and A. Miserez*. (2017). Preventing Mussel Adhesion Using Lubricant-Infused Materials. Science, 357(6352), 668–673.
- S. Amini, M. Tadayon, S. Idalapati, and A. Miserez*. (2015). The Role of Quasi-Plasticity in the Ultra Contact Damage Tolerance of the Stomatopod Dactyl Club. Nature Materials, 14, 943-950.
- YP. Tan, S. Hoon, P. Guerette, W. Wei, A. Ghadban, C. Hao, A. Miserez*, J.H. Waite*. (2015). Infiltration of Chitin by Protein Coacervates Defines the Squid Beak Mechanical Gradient. Nature Chemical Biology, 11(9), 488–495.
- P.A. Guerette, S. Hoon, Y. Seow... and A. Miserez*. (2013). Accelerating the Design of Biomimetic Materials by Integrating RNA-seq with Proteomics and Materials Science. Nature Biotechnology, 31(10), 908-915.
- J.C. Weaver#, S. Milliron#, A. Miserez# et al. (2012). The Stomatopod Dactyl Club: A Formidable Damage-Tolerant Biological Hammer. Science, 336, 1275-1280.