|Asst Prof Abdulkadir C. Yucel||(i) Fast frequency and time domain electromagnetic simulators with applications to the VLSI/microwave/terahertz circuits, biomedical, photonics, wireless channel characterization in tunnels, and analysis of inhomogeneous negative permittivity media.
(ii) Uncertainty quantification for electromagnetic analysis on complex platforms
|Assoc Prof Andrew James Kricker||Prof. Kricker's most significant research interest lies in the mathematical ramifications of current developments in mathematical and theoretical physics. To be precise, he is interested in the ramifications of certain developments in quantum field theory and quantum gravity in the fields of topology, algebra, and combinatorics. Prof. Kricker's particular speciality is in so-called "quantum topological invariants". These are invariants of knots, 3-manifolds, and various other low-dimensional topological structures, that arise from Topological Quantum Field Theories. More generally, he has a considerable general interest in the fields that surround this topic: knot theory, the theory of low-dimensional manifolds, Lie algebras, Hopf algebras, representation theory, homological algebra, algebraic combinatorics, and so on.
|Prof Atul N. Parikh||Membrane biophysics
biologically inspired materials
synthetic chemical biology
|Asst Prof Bent Weber||• Atomic and electronic structure of two-dimensional and topological materials
• Quantum information processing science and technology
• Nanoelectronic and quantum device physics
• Low-temperature scanning probe microscopy
• Atomic manipulations and lithography
|Prof Boris Lukiyanchuk||Prof. Lukiyanchuk's significant research interests are related to Laser - matter interactions, Chemical processing with lasers, Nonlinear phenomena, Selforganization, Laser-ablation, Nanoclusters, Photo modification in polymers, Laser Cleaning, Plasmonics, Metamaterials, Nanoscopy, Nanooptics, Fano resonances in plasm
|Prof Carlo Sirtori||My research activities are mostly dedicated to light and condensed matter interaction, with a special emphasis on semiconductor low dimensional-structures. The design and realisation of new devices based on the fundamental laws of quantum mechanics are always at the centre of my interests. My continuous interactive dialog with industrial partners has driven these investigations towards the matching of fundamental research with long-term technological needs. A clear example of the mixing between fundamental and applied is the quantum cascade (QC) laser where quantum engineering of artificial electronic and photonic potentials blend in with the realisation of optoelectronic devices.
At present my main research interest are:
- Quantum devices bases on the strong and ultra-strong light matter interaction
- Superradiant devices
- High frequency modulation of QC laser
- THz QC lasers
- Antenna coupled to micro-cavities detectors
- Quantum phenomena in LC-circuit resonators
|Assoc Prof Cesare Soci||Our research embraces several key areas of nanoelectronics and nanophotonics, including organic semiconductors and plasmonic materials, as well as new ideas on specialty optical fibers and “cognitive photonic networks”. We are particularly interested in fundamental properties of materials emerging from small dimensionality, large interface area, hybridization and artificial nanostructuring.
|Assoc Prof Chai Gin Boay||Composite Materials & Structures, Buckling and Failure of Structures,
Practical Application of Finite Element softwares (ANSYS, ABAQUS, MARC/MENTAT).
|Asst Prof Chang Wonkeun||- Ultrafast light-matter interactions
- Light source development in mid-infrared and vacuum-ultraviolet
- Ultrashort pulse generation
- Complex dynamics in pulsed laser systems
|Asst Prof Chen Gang||The overall goal of my research group is to employ cutting-edge biophysical techniques to better understand the structures and the physical-chemical properties of RNAs and RNA-ligand complexes to provide deeper insight into and to facilitate precise control of the diverse biological functions involving RNA. We aim to use the fundamental knowledge to fight neurodegenerative diseases, cancers, bacterial and viral infections by designing and discovering novel therapeutic ligands targeting RNA. To approach the challenging goals, we have assembled a multidisciplinary team with expertise ranging from molecular biophysics, structure biology, computation, chemical synthesis, cell biology, to medical healthcare. The research projects of current interests are: (1) characterizing the molecular recognition interactions (e.g., hydrogen bonding and aromatic base stacking) accounting for structure, stability, and dynamics of RNA structural building blocks such as internal loops, hairpins, triplexes, and pseudoknots, (2) probing the complex energy landscapes of RNA folding and assembly with protein, and (3) designing and discovering therapeutic ligands (small molecules, oligonucleotides, peptides, peptide nucleic acid, etc.) targeting RNA. We employ various conventional and cutting-edge biophysical and biochemical techniques including laser optical tweezers, NMR, UV-Vis, fluorescence, SPR, gel electrophoresis, PCR, chemical synthesis of modified oligonucleotides and peptides, in vitro transcription, protein expression, and cell culture assay. The research experience in the laboratory will help the students to grasp fundamental knowledge and experimental skills, to develop learning skills such as rigorous reasoning and innovative thinking, and to be able to ask and answer important questions within and beyond chemical and molecular sciences.
Ru Ying Puah,= Huan Jia, = Manikantha Maraswami,= Desiree-Faye Kaixin Toh,= Rya Ero,= Lixia Yang, Kiran M. Patil, Alan Ann Lerk Ong, Manchugondanahalli S. Krishna, Ruimin Sun, Cailing Tong, Mei Huang, Xin Chen, Teck Peng Loh, Yong-Gui Gao, Ding Xiang Liu,* and Gang Chen,* (2018) Selective Binding to mRNA Duplex Regions by Chemically Modified Peptide Nucleic Acids Stimulates Ribosomal Frameshift. Biochemistry (Invited for a special issue of Future of Biochemistry), In press.
Manikantha Maraswami, Sreekumar Pankajakshan, Gang Chen* and Teck-Peng Loh* (2017) Palladium-Catalyzed Direct C-H trifluoroethylation of aromatic amides, Org Lett, 19, 4223–4226
Hongzhong Chen, Huan Jia, Huijun Phoebe Tham, Qiuyu Qu, Pengyao Xing, Jin Zhao, Soo Zeng Fiona Phua, Gang Chen,* and Yanli Zhao,* (2017) Theranostic Prodrug Vesicles for Imaging Guided Co-Delivery of Camptothecin and siRNA in Synergetic Cancer Therapy, ACS Appl. Mater. Interfaces, 9, 23536–23543
Desiree-Faye Kaixin Toh,= Kiran M. Patil,= and Gang Chen,* (2017) Sequence-specific and selective recognition of double-stranded RNAs over single-stranded RNAs by chemically modified peptide nucleic acids (Invited Methods Article), J Vis Exp, In press, (= These authors contributed equally to this work).
Zhensheng Zhong, Lixia Yang, Haiping Zhang, Jiahao Shi, Jeya Vandana, Do Thuy Uyen Ha Lam, René C. L. Olsthoorn, Lanyuan Lu, and Gang Chen* (2016) Mechanical unfolding kinetics of the SRV-1 gag-pro mRNA pseudoknot: possible implications for −1 ribosomal frameshifting stimulation, Sci Rep, 6, 39549.
Toh, D.-F.,= Devi, G.,= Patil, K.M., Qu, Q., Maraswami, M., Xiao, Y., Loh, T.-P., Zhao, Y.,* and Chen, G.* (2016) Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine-purine inversion site of an RNA duplex. Nucleic Acids Res, 44, 9071-82
Jiazi Tan, Jia Xin Jessie Ho, Zhensheng Zhong, Shufang Luo, Gang Chen, and Xavier Roca* (2016) Noncanonical registers and base pairs in human 5’ splice-site selection. Nucleic Acids Res, 44, 3980-21