Research Categories

Nanotechnology & Nano-Science

Nanotechnologycluster

As one of the priority research areas, NTU has many strong research teams working on the nanoscience and nanotechnology such as NanoCluster and NanoFrontier as well as many other research groups speacialising in specific areas of nanotechnology and nano science.

The research group of nanotechnology emphasizes its research on fuel cell technology, applied catalysis and reaction engineering, functionalized polymeric materials and  nanocomposite materials for biosensors and

pharmaceutical applications. The state-of-the-art analytical and characterization facilities available provide support for cutting-edge research in areas.

The nanoscale-initiatives in nanobiotechnology group at NTU bring together researches concerned with the development of nanomaterials, including nanomagnetic carriers, for bioengineering and life sciences applications. Other areas of interest include biosensors, biomimetics, biophotonics and bioimaging. These studies are expected to lead to significant improvements in a wide variety of products and processes in the biotechnology space. Specific projects include nanomagnetic particles for cancer treatment and photonic devices for biomedical applications.

The nanoelectronics group addresses the development of new materials, processes and devices for the next generation of electronic devices. Key research and academic programs include synthesis of materials, processes, packaging and reliability. Research in nanoelectronics includes materials used for the 65nm node and beyond, high-k gate dielectric materials, Si/SiGe devices and substrates, and finally sub 500nm materials development for packaging applications.

nanoenergy
Thin film deposition and characterization for dielectric films, barrier layers, and interconnect structures is also pursued. Integration and reliability of these materials such as electro-migration, stress migration, dielectric breakdown, thin film transistors, organic photovoltaics and memory devices are actively researched.

The nanoelectronics group addresses the development of new materials, processes and devices for the next generation of electronic devices. Key research and academic programs include synthesis of materials, processes, packaging and reliability. Research in nanoelectronics includes materials used for the 65nm node and beyond, high-k gate dielectric materials, Si/SiGe devices and substrates, and finally sub 500nm materials development for packaging applications. Thin film deposition and characterization for dielectric films, barrier layers, and interconnect structures is also pursued. Integration and reliability of these materials such as electro-migration, stress migration, dielectric breakdown, thin film transistors, organic photovoltaics and memory devices are actively researched.

nanodevice The projects in nano photonics cover the area of optoelectronics devices and packaging, nano metrology, and finally photonic band gap materials. Arrayed waveguide gratings, transceiver assemblies used in optical networking units have been successfully fabricated and characterized. Optics based novel nano characterization techniques for non-contact and whole field characterization of materials have also been developed.

The projects in nano magnetics predominantly aim to synthesize nano materials for improved magnetic performance. Some projects deal with the production of nano particles for a variety of applications while the others investigate the production of nano-structured materials or nanocomposites. They either attempt to optimize the production processes in order to obtain the required nano material or manipulate the material structure and chemistry at nano-scale to achieve the required nano structure. Thus there is a mixture of process development and application development.

New applications of nanomaterials are being developed for the purification of chemical compounds or to modify the surface properties of manufacturing tools.

The nanomaterials group at NTU aims to develop more efficient synthesis methods and novel application of nanomaterials. For synthesis a preferred research direction follows a top-bottom approach, where nanomaterials are precisely defined from a bulk material using beam of ions (FIB) or plasma etching techniques (DRIE) with nanoparticles used as a mask. A bottom-up synthesis approach is also followed, based on the growth of nanocrystals.

nanomaterials
New applications of nanomaterials are being developed for the purification of chemical compounds or to modify the surface properties of manufacturing tools.



Related Links:
Nanotechnology, School of Chemical & Biomedical Engineering
Nano-Electronics and Interconnects, School of Materials Science & Engineering

Rare Earth Nano-Materials, School of Materials Science & Engineering


 Name Research Interests
Goh, Kheng Lim Physical properties of connective tissues; Mechanisms of biological ageing in the extra-cellular matrices of connective tissues, fibril reinforcing composites; Carbon nanotubes; nuclear medicine
 Ma, Jan Functional materials;  Nanomaterials and constitutive modeling of densification of composite materials
Ramanujan, Raju Development of nanomaterials, particularly nanomagnetic materials for a variety of applications including bioengineering, data storage and power electronics applications
Tan, Lay Poh Nanomaterials and Biomaterials such as biodegradable polymers, biopolymer blends, drug delivery and synthesis of biodegradable tissue adhesives
Yuan, Larry Xiacong Micro- and nano-scale optics (MNO); Optical trapping and manipulation (OTM); Surface plasmon resonance (SPR); Optical imaging and super-resolution; Applications of MNO; OTM and SPR in biotechnology
Zhang, Dao Hua Semiconductor materials, devices and physics; Quantum well, wire and dot structures, devices and arrays; New nano-scaled materials and devices for low and room temperature infrared detection
XYZ Nano layer materials, nano electronics, xxxx, xxxx,  
   

NameResearch Interests
Asst Prof (Steve) Cuong Dang- OptoElectronic Devices - Nano-Photonics - LEDs, Lasers, Quantum Emitters - Nano-Materials
Dr Alessandra BonanniBiosensor technologies Biosensors are analytical tools which combine a biorecognition agent which provides selectivity and a transducer that confers sensitivity and can convert the biorecognition event into a measurable electronic signal. The advantage of using biosensor over traditional techniques is represented by their low costs, small dimensions, portability, and fast response. The different areas for potential biosensor applications are mainly medical diagnosis, environmental monitoring and food analysis. DNA analysis DNA analysis is of extreme importance to solve problems of different nature such as investigation on genetic diseases, detection of food and water contamination by microorganism, studies on breeding origins or tissue matching, and solution of forensic issues. The techniques for genome identification are nowadays mainly based on DNA sequencing by using fluorescent labels and optical detectors. They require a few days for the analysis to be completed and the costs are prohibitive to the general public. Demand has never been greater for innovative technologies which can provide fast, inexpensive and reliable genome information. The focus of my research is on the development of analytical tools (biosensors) for the rapid, reliable and low cost identification of DNA sequences. In order to achieve that, different electrochemical techniques are used for the detection of the analytical signal. The developed biosensors are based on various platforms (such as gold, carbon and silicon) and different nanomaterials (i.e. gold nanoparticles, graphene nanoplatelets and several quantum dots) are employed for the amplification of the obtained signal and the improvement of detection limit. The final step of this work is the application of the developed genosensor to real sample analysis. Once this second part is successfully accomplished, the analytical tool could be eventually integrated into a DNA amplification process, resulting in a portable device for point-of-care diagnostic tests and for very sensitive detection of SNPs correlated to different diseases. Food Analysis This field includes research in the two following areas: - Application of DNA genosensors to identify of DNA sequences correlated to bacteria involved in food contamination (i.e. Salmonella spp, Listeria monocytogenes, Escherichia coli) - Development of electrochemical biosensors for the detection of antioxidant capacity of food and beverages
Assoc Prof Alfred Tok Iing Yoong1) Carbon-based Field-Effect Transistor Sensors The biosensors market, which is currently at USD 9.9 billion, is expected to reach USD 18.9 billion in 2019 (GIA Report, 2014) propelled by the growing population and health issues. Our group capitalizes on this emergent market and researches on disposable and low-cost sensor suitable for real-time sensing in field conditions. Our group focuses on sensors for biological and gas detection applications. 2) Synthesis of Nanostructured Materials using Atomic Layer Deposition (ALD) Atomic layer deposition (ALD) has evolved to be a unique tool for nanotechnology with atomic level control of the depositions, 3D conformity and homogeneity. Film depositions can be realized for complex non-planar topographies for a wide range of applications such as energy conversion and storage, nanoparticle catalysts, nanostructures for drug delivery, gas separations, sensing, and photonic applications. Our group focuses on ALD materials for solar cell, hydrogen generation and smart window applications. 3) Hard & Tough Materials for Ballistic Protection Application The next generation of military vehicular and soldier system requires light-weight materials with high strength-to-weight ratio. Our research focuses on the synthesis and densification of nanostructured materials & desired composite architecture to significantly raise the ballistic protection capability. The B-C-N-O group of compounds are potential candidates to form novel materials for ballistic protection application as they inherent the unique properties from both boron nitride and boron carbide which are known for their light weight, high hardness, low friction coefficient and high wear resistance. Prof Tok leads a team of collaborators in armour material research ranging from high temperature synthesis of novel superhard materials and consolidation by state-of-the-art Spark Plasma Sintering to advanced characterisation techniques such as depth of penetration test using Two-Stage Light-Gas Gun. 4) Institute for Sports Research Our group is involved in the Institute for Sports Research, working on the damping property of midsoles which is based on carbon nanotube (CNT). CNT’s high aspect ratios (length/diameter) is particularly desirable for mechanical reinforcement, and it is found that the vertical aligned (VA)CNTs perform well in damping, to dissipate the energy absorbed under compression (Figure 7). Our present job is to tune the damping property of VACNT by adjusting the length, diameter and area density etc. parameters and try to reinforce the polymer with VACNT to fabricate midsole material with better cushion property. 5) NRF-CREATE In accordance with the objectives of the Energy Thrust Program of the NRF-CREATE Project, our group is focused on the design and synthesis of highly functional nanomaterials, which enables energy harvesting and conservation. Recently, novel graphene oxide synthesized nanoballs and nanoflowers were synthesized. These exhibit potentials for supercapacitors and energy applications. In general, these activities results in above 50 publications, 17 patent applications and projects discussions with companies regarding commercialization possibilities.
Assoc Prof Ali MiserezStructural properties of biological materials from the macro-scale to the nano-scale Multi-scale structural and mechanical properties of biological materials, including biominerals. Elastomeric and structural properties of bioelastomers Protein chemistry of sclerotized hard-tissues from marine organisms, such as Cephalopod Single-molecular force spectroscopy of structural and elastic proteins Underwater adhesion mechanisms of adhesive proteins Biofouling RNA-sequencing and proteomics of extra-cellular biological materials Advanced Metal/Ceramic composites Experimental Fracture Mechanics
Assoc Prof Ang Diing Shenp1. Reliability physics and characterization of nanoscale transistors (negative-bias temperature instability, hot-carrier effects, gate oxide breakdown, low frequency/RF noise, metal gate/high-kappa gate stack, non-volatile memories, silicon-on-insulator transistors, nanowire devices etc.) 2. Nano-characterization techniques (conductive atomic force microscopy, high-resolution transmission electron microscopy and associated anaytical techniques for alternative gate dielectrics, nanowire devices etc.) 3. Characterization of novel devices (e.g. tunneling FETs, novel memories etc.)
Asst Prof Anupam ChattopadhyayComputing Architecture Design Automation Security Emerging Technologies
Assoc Prof Aravind Babu DasariDr Dasari’s major research emphasis is on the development of in-depth understanding of the various facets of processing-structure-property relations in hybrid polymer nanocomposites to achieve synergistic properties for different end applications. These facets include: 1. Thermal stability and flame retardancy (with eco-benign agents) 2. Functional properties (electrical/thermal conductivities, biodegradability and UV shielding) 3. Electrospinning techniques 4. Wear/scratch damage at different scales (macro/micro/nano) 5. Deformation and Fracture mechanisms 6. Active food packaging
Assoc Prof Atsushi GotoPolymer Chemistry and Polymer Materials 1) Controlled syntheses of polymers 2) Development of new living radical polymerization via organic catalysis 3) Creation of new advance polymer materials using structurally controlled polymers
Asst Prof Bent Weber• Atomic and electronic structure of two-dimensional and topological materials • Quantum information processing science and technology • Nanoelectronic and quantum device physics • Low-temperature scanning probe microscopy • Atomic manipulations and lithography
Prof Bo Gunnar LiedbergThe research interests of Prof. Bo Liedberg can be divided into three main areas Surface Chemistry and Self Assembled Monolayers This part of the research concerns fundamental studies of adsorbates and ultrathin molecular architectures, like Self-Assembled Monolayers (SAMs), on solid supports. The group was very early in studying self-assembly of substituted alkylthiols on gold substrates. A key activity has been to study temperature driven phenomena occurring in such assemblies as well as in adsorbed layers on top such SAMs. Oligo(ethylene glycol) and oligosaccharide SAMs have attracted considerable attention, both experimentally and theoretically, because of their structural characteristics and advantageous properties in contact with biofluids. Another area concerns interfacial water and ice. Temperature programmed studies have been undertaken to improve the understanding of the nucleation and microscopic wetting behavior of water/ice. The complexity of the SAMs has increased over the years and we are today focusing on architectures based on SAMs bearing multivalent chelator heads, helix-loop-helix polypeptides and receptor functions. Bioinspired and Biomimetic Nanoscience This research concerns the development of nanoscale architectures fabricated using either top-down or bottom-up protocols (or a combination of both). We are, for example, developing plasmonic arrays based on 100 nm gold nano dots on silicon and glass surface for amplification of optical fluorescence signals, so-called metal enhanced fluorescence (MEF). We are also developing composite materials based on a combination of de novo designed peptide scaffolds, planar surfaces and nanoparticles of controlled size and shape. A novel concept based on peptide folding has been used for controlled assembly of gold nanoparticles. The group is also involved in the development of Dip Pen Nanolithography (DPN) for patterning of surfaces on the 30-100 nm length scale. This work is performed jointly with a previous student of the group who nowadays is setting up a nanolaboratory at the Institute of Physics, Vilnius. We are also involved in several EC projects where different types of micro- and nanoscale patterning tools are employed for production of coatings for biofouling, sensing and biomedical applications. Optical Biosensors, micro- and nanoarrays The group has a long experience in developing optical transducers for biosensing application. We were the first to demonstrate the use of surface plasmon resonance for studies of bioaffinity interactions at surfaces, a technology that today form the backbone in SPR/Biacore instruments developed for biospecific interaction analysis (BIA). We are today using it in combination with ellipsometric interrogation and imaging optics for microarraying, and in combination with nanoparticle for studies optical enhancement phenomena. This includes, for example, microarray chips for protein multiplexing. The group is also working on the development of generic biochips for studies of ligand-receptor binding. Besides working on microarray fabrication for protein detection and analysis we are also developing biochips for the safety and security area. Selected publications 1. Tinazli, A., Tang, J., Valiokas, R., Picuric, S., Lata, S., Piehler, J., Liedberg, B., Tampe, R., Chem. Eur. J. 11, 5249-5259 (2005). 2. Aili, D., Enander, K., Tai, F-I., Baltzer, L., Liedberg, B., Angew. Chem., 120, 5636-5638 (2008). 3. Aili, D., Enander, K., Baltzer, L., Liedberg, B., Nano Letters, 8, 2473-2478 (2008). 4. Andersson, O., Ulrich, C., Björefors, F., Liedberg, B., Sensors&Actuators B: Chemical, 134, 545-550 (2008). 5. Klenkar, G., Liedberg, B., Anal. Bioanal. Chem. 391, 1679-1688 (2008). 6. Aili, D., Selegård. R., Baltzer, L., Enander, K., Liedberg, Small, 5, 2445-2452 (2009). 7. Lee, H.-H., Ruzele, Z., Malysheva, L., Onipko, A., Gutes, A., Björefors, F., Valiokas, R., Liedberg, B., Langmuir, 25(24), 13959–71 (2009).