Nanyang Technology University

Academic Profile
Assoc Prof Surajit Bhattacharyya

Associate Professor 
Division of Structural Biology & Biochemistry 
School of Biological Sciences 
College of Science 



Email: SURAJIT@ntu.edu.sg
Phone: (+65)63167997 
Office: SBS-02s-78 
Education
  • PhD(Molecular Biophysics) Indian Institute of Science 1998
  • MSc(Biotech) Madurai Kamaraj University 1992
  • BSc(Ag.)(Hons) Bidhan Chandra Agricultural University 1989
Biography
Prof Surajit Bhattacharyya is currently in the School of Biological Sciences since 2005. He received his Bachelor degree in Agricultural Sciences from India, Master in Biotechnology from India and Ph.D. degrees from the Indian Institute of Science, India respectively. His research interests include Strutural Biology using NMR spectroscopy, and drug design. He has done significant research work his research areas and published over 23 top quality international conference and journal papers. He has been often invited as a referee and reviewer for a number of premier journals, including Biochemistry, Langumur, Biopolymers, BBA etc.
Research Interests
Structural Dissection of Scaffolding Protein and Its Interactions with Kinases
SAM-SAM Interactions in MAPKKK Activating Ste11/Ste50 Complex
Interactions of Integrin Tails with Effector Proteins
Designed Peptide Antagonists against Endotoxin: A structure-based approach to develop antisepsis and antimicrobial drugs.
Structure and Activity of Cathelicidin Family of Antimicrobial and Antiendotoxic Peptides.
Research Grant
  • A*STAR Biomedical Research Council (2007-)
  • Academic Research Fund Tier 1 (2011-2013)
  • Academic Research Fund Tier 2 (2011-2014) [by Ministry of Education (MOE)]
  • University Research Committee - Start Up Grant (2006-)
Current Projects
  • NMR Microspectroscopy Using Microprobe Chips
  • Solution structures of peptides and protein fragments in complex with lipopolysaccharide by nuclear magnetic resonance (NMR) spectroscopy : Towards a rational development of anti-sepsis drugs
  • Stability, folding and interactions of the sterile alpha-motifs (SAM Domains) from signaling cascades of yeast
  • Structure and Dynamics of Membrane active Viral Proteins by NMR Spectroscopy
  • Structures and Interactions of Potent Antimicrobial Peptides with Lipopolysaccharide
  • The molecular and structural bsis of leukocyte b2 integrins signalling
Selected Publications
  • A Bhunia, A, Ramamoorthy, S, Bhattacharjya. (2009). Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR. Chemistry - A European Journal, .
  • A. Bhunia, H. Mohanram, P.N. Domadia, J. Torres, and S. Bhattacharjya. (2009). Designed beta-boomerang antiendotoxic and antimicrobial peptides: Structures and activities in lipopolysaccharide. Journal of Biological Chemistry, .
  • A Bhunia, H Mohanram, S Bhattacharjya. (2009). NMR structural studies of the Ste11 SAM domain in the dodecyl phosphocholine micelle. Proteins: Structure, Function, and Bioinformatics, 74, 328-343.
  • A, Bhunia, H, Mohanram, S, Bhattacharjya. (2009). Lipopolysaccharide bound structures of the active fragments of fowlicidin-1, a cathelicidin family of antimicrobial and antiendotoxic peptide from chicken, determined by transferred nuclear Overhauser effect spectroscopy. Biopolymers: Peptide Science, 92, 9-22.
  • A Bhunia, X, Tang, H, Mohanram, S Tan, S, Bhattacharjya. (2009). NMR solution conformations and interactions of integrin L2 cytoplasmic tails. Journal of Biological Chemistry, 284, 3873-3884.
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