| Asst Prof Loo Say Chye Joachim
Assistant Professor
Division of Materials Technology
School of Materials Science & Engineering
College of Engineering
Email: JOACHIMLOO@ntu.edu.sg
Phone: (+65)6790 4603
Office: N4.1-01-04a |
| Education |
- PhD Nanyang Technological University 2005
- BASc(Matl.Eng)(Hons) Nanyang Technological University 2001
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| Biography |
| Dr Joachim Loo is currently an Assistant Professor in the School of Materials Science and Engineering since 2005. He graduated with a Bachelor degree in Applied Science (Materials Engineering) and received his Ph.D. degree from NTU. He later spent some time in Mayo Clinic (USA) before joining NTU as a faculty member. His research interests include biomaterials, controlled release and targeted delivery, and have published more than 20 peer-reviewed journal and conference papers, including several in Biomaterials. He has been often invited as a reviewer for a number of premier conferences and journals, including Biomaterials, Journal of Controlled Release and Polymer. He is also the Guest Editor of the journal, Biofactors. Dr. Joachim Loo is currently an Executive Committee Member of the Materials Research Society of which he was a member since 2002. |
| Research Interests |
I. Nano-Biomaterials for Biomedical Applications
1) Developing multi-functional nanoparticles for bioimaging and cancer therapy ? Collaboration with Prof Stephen J Russell and Prof Peng Kah-Whye, Mayo Clinic, USA.
2) Targeted dendrimers for cardiovascular repairs ? Collaboration with Dr Moe Kyaw Thu, National Heart Centre, Singapore.
3) Surface modification of nanoparticles using peptidomimetic polymers ? Collaboration with Prof Philip Messersmith, Northwestern University, USA.
4) Stealthy nanoparticles for targeted delivery ? Collaboration with Prof Freddy Boey and Prof Subbu Venkatraman, NTU, Singapore.
II. Biodegradable Polymers for Biomedical Applications
1) X-ray CT-scan imaging of biopolymers ? Collaboration with Prof Zbigniew Stachurski, Australia National University, Australia.
2) FTIR and Raman imaging of biomaterials ? Collaboration with Dr Effendi Widjaja, ICES, Singapore.
3) Laser modification of biomaterials ? Collaboration with Dr David Low and Dr Wang Xincai, SIMTech, Singapore.
4) Drug release, controlled degradation and surface modification of multi-layered biopolymer films ? Mr Alfred Chia, Amaranth Medical Pte Ltd, Singapore.
5) Multi-layer biodegradable microparticles for sustained release of drugs ? Prof Shabbir Moochhala, Defense Science Organization, Singapore.
III. Tissue Engineering
1) Effects of sub-micron sized debris from hip-joint implants on bone resorption ? Collaboration with Prof Wilson Wang, NUH, Singapore.
2) Mesoporous biomaterials for bone tissue engineering ? Collaboration with Prof Wilson Wang, NUH, Singapore.
3) Determination of resorption surface area on bone samples using photonics ? Collaboration with Prof George Chen, EEE, NTU, Singapore. |
| Research Grant |
- Academic Research Fund Tier 1 (2008-)
- NRF Competitive Research Program (2008-)
- National Medical Research Council (2010-)
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| Current Projects |
- Biodegradable Cardiovascular Implants: Novel Biodegradable Polymers
- Bone-targeting Nanomedicine for Treating Osteomyelitis
- Stealth Hydroxyapatite Nanoparticle for Targeted Delivery And Bioimaging
| Selected Publications | - YLJ Han, SCJ Loo, NT Phung, HT Ong, SJ Russell, KW Peng, F Boey, J Ma. (2008). Controlled size and morphology of EDTMP-doped hydroxyapatite nanoparticles as model for 153samarium-edtmp doping. Journal of Materials Science: Materials in Medicine, .
- Say Chye Joachim Loo, Yiwei Eva Siew, Shuhui Ho, Freddy Yin Chiang Boey, Jan Ma. (2008). Synthesis and hydrothermal treatment of nanostructured hydroxyapatite of controllable sizes. Journal of Materials Science: Materials in Medicine, 19(3), 1389-1397.
- Ong HT, Loo JSC, Boey FYC, Russell SJ, Ma J, Peng KW. (2008). Exploiting the high-affinity phosphonate-hydroxyapatite nanoparticle interaction for delivery of radiation and drugs. Journal of Nanoparticle Research, 10, 141-150.
- S.C. J. Loo, C. P. Ooi, FYC Boey. (2005). Influence of electron beam radiation on the hydrolytic degradation behaviour of poly(lactide-co-glycolide) (PLGA). Biomaterials, 26(18), 3809-3817.
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