| Assoc Prof Xing Bengang Deputy Head (Undergraduate Studies & Admissions), Division of Chemistry & Biological Chemistry Associate Professor Division of Chemistry & Biological Chemistry School of Physical & Mathematical Sciences College of Science
Email: BENGANG@ntu.edu.sg Phone: (+65)63168758 Office: SPMS-CBC-04-20 |
| Education |
- PhD Nanjing University 2000
- MS Guangxi Normal University 1997
- BS Xingjiang Normal University 1994
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| Biography |
| Prof. XING Bengang is currently in the Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences since early of 2006. He received his Bachelor degree in Chemistry from BS Xingjiang Normal University 1994, and Ph.D. degrees from the Nanjing University respectively. His research interests include nanobiotechnology, and fluorescent imaging. He has done significant research work his research areas and published over 30 top quality international conference and journal papers (such as Journal of the American Chemical Society; Angewandte Chemie International Edition etc). He has been often invited as a referee and reviewer for a number of premier conferences and journals, including Angewandte Chemie International Edition; Chemsitry Letters etc. Dr. XING Bengang is a member American Chemical Sciety |
| Research Interests |
Dr. XING's research interests will be highly interdisciplinary in the interface of nano-biotechnology, fluorescent imaging, Biomaterials as well as medicinal chemistry. Specific aims of ours are to integrate the basic knowledge and techniques to design, develop and identify the small molecules, natural products, peptides and/or their analogues for probing some special biological molecular. We are also interested in development of new functional nanomaterials for enzyme detection, drug delivery and clinical diagnosis.
1. Nano-biotechnology: Developments of nano-particles (such as gold, silver, magnetic particles and quantum dots etc) and/or carbon nanotube based biomaterials for drug delivery and biomolecular imaging.
2. Fluorescent imaging: Design and synthesis of new fluorescent probes for efficnet detection of biological active molecules (?-galactosidase, proteases and ?-lactamase etc).
3. Biomaterials: Design, synthesis and characterization of new transporters and/or the peptides based hydrogels for biomedical application. |
| Research Grant |
- A*STAR Science and Engineering Research Council - Public Sector Funding (2012-)
- Academic Research Fund Tier 1 (2006-) [by MOE]
- Academic Research Fund Tier 1 (2011-)
- Start Up Grant (2005-)
- Supplementary Equipment Purchase (2006-) [by MOE]
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| Current Projects |
- Antimicrobial Materials Against Drug-Resistant Bacteria: Design, Spectroscopic Characterization and Computational Modelling
- Design and Preparation of Cell Permeable Fluorescent Probes for Imaging of Beta-Lactamase In Vitro and In Vivo
- Design and preparation of novel lanthanide and nano-particle based fluorescent tools for real time monitoring of Beta-lactamase
- Hydrogen Bonding Interaction Between Antibiotics and Peptide Precursors on Bacterial Surfaces: An Investigation Using Single-Molecule Fluorescence Detection Techniques
- Photoactive and Biodegradable Inorganic Nanoparticle Conjugates and Their Applications in Bioluminescent Imaging
| Selected Publications | - Shao Q, Xing BG*. (2010). Photoactive molecules for applications in molecular imaging and cell biology. Chemical Society Reviews, .
- Liu RR, Teo WL, Tan SY, Xing BG*. (2010). Metallic Nanoparticles Bioassay for Enterobacter cloacae P99 B-lactamase activity and inhibition screening.. The Analyst, .
- Liu HG, Zhang XF, Xing BG, Han P, Gambhir SS, Cheng Z*. (2010). Radiation Luminescence excited quantum dots for in vivo multiplexed optical imaging. Small, .
- Aw JX, Shao Q, Yang YM, Xing BG*. (2010). Synthesis and characterization of 2-(2'-hydroxy-5'-chlorophenyl)-6-chloro-4(3H)-Quninazoline based fluorogenic probes for cellular imaging of monoamine oxidases.. Chemistry - An Asian Journal, .
- HJ Feng, YM Yang, YM You, GP Li, J Guo, T Yu, ZX Shen, T Wu, BG Xing. (2009). Simple and Rapid Synthesis of Ultrathin Gold Nanowires, Their Self-Assembly and Application in Surface-Enhanced Raman Scattering. Chemical Communications, (15), 1984-1986.
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