| Prof Subramanian Venkatraman
Chair, School of Materials Science & Engineering
Division of Materials Technology
School of Materials Science & Engineering
College of Engineering
Email: ASSUBBU@ntu.edu.sg
Phone: (+65)6790 4259
Office: N4.1-02-05 |
| Education |
- PhD Carnegie Mellon University 1981
- MSc Indian Institute of Technology, Chennai 1976
- BSc(Hons) Bangalore University 1974
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| Biography |
| Dr.Subbu Venkatraman has a PhD in Polymer Chemistry from Carnegie-Mellon University. He has spent about 15 years in biomedical R&D in the USA, working with various applications of polymeric biomaterials. He held a senior position in R&D at Alza Corporation prior to joining NTU as Associate Professor in 2000. Since then he has published extensively in the field of biomaterials, with a total of 130 publications, and a citation count of 1300+ and a h-index of 23. He also holds 20 issued US patents in biomaterials/drug delivery, and 5 of these have been translated into products. He is concurrently the Director of the Ocular Therapeutic Engineering Centre, as well as Dy Director of the Nanyang Institute of Technology in Health & Medicine, and works closely with clinicians from Singapore and world-wide. |
| Research Interests |
| Research is focussed on the applications of polymeric biomaterials in medicine. In particular, research areas include biodegradable stents, injectable drug delivery systems and gene delivery. Controlled release of drugs to the eye and the cardiovascular system are the primary end applications. Cancer therapy using "stealth" particles also forms a significant component of the research activities. |
| Research Grant |
- A*SERC Singapore-China JRP Call for Proposals (2011-)
- Academic Research Fund Tier 1 (-)
- Academic Research Fund Tier 1 (2013-)
- Academic Research Fund Tier 2 (-)
- Economic Development Board - Biomedical Sciences Proof of Concept (2007-)
- NRF CREATE (2009-)
- NRF Competitive Research Program (2008-)
- NRF Competitive Research Program (2008-2013)
- NRF Proof of Concept (2010-)
- NTU Internal Funding – Nanyang Institute of Technology in Health & Medicine (NITHM) (2011-)
- NTU-NHG Innovation Collaboration Grant (2013-)
- Singapore General Hospital Research Grant (2013-)
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| Current Projects |
- A New Glaucoma Drainage Device with Sustained Drug Elution
- A new biodegradable, sustained-release drug delivery system in a rabbit model
- Amaranth Medical 1
- Amaranth Medical 2
- Biodegradable Cardiovascular Implants
- Biodegradable Cardiovascular Implants: Biodegradable Elastomers
- Biodegradable Cardiovascular Implants: Cell-Biomaterials Interactions II
- Biodegradable Cardiovascular Implants: Surface Functionalization for Cell Growth
- Bone-targeting Nanomedicine for Treating Osteomyelitis
- Controlled Drug Delivery From Core-Shell Nanofibers in Polymeric Matrices (NTU-Technion)
- Development and application of sustained drug release technology for the delivery of nucleic acid molecules for the prevention of post-operative scarring in glaucoma
- Development of novel bioabsorbable drug-eluting ventilation tube for chronic middle ear infection
- Drug Delivery Systems for Glaucoma and Cornea
- Drug-Eluting Balloons (DEB) Controlled Delivery through Nanoparticulate Coating
- Key technologies for developing microorganisms-derived hyaluronic acid for biomedical applications
- Nanostructured Hydrogels: Characterization & Applications
- Nanostructured hydrogels for Cardiac Tissue Engineering
- Novel drug delivery platform based on coated ureteral stents for reducing ureteral fibrosis and strictures
- Self-Expanding Biodegradable Heart Plug
- Synthesis and Characterization of Biodegradable Thermoplastic Elastomers
- The Regenerative Medicine Initiative in Cardiac Restoration Therapy Research Programme
- Vesico-Urethral Connector
| Selected Publications | - Xu Wen Ng, Yingying Huang, Subbu S Venkatraman and Freddy Boey. (2013). Controlled release of cardiovascular peptides from biodegradable patches. 25th European Conference on Biomaterials.
- Soo Ghim Lim, S. Jeson Sangaralingham, Syed Ameenuddin, Fernando L. Martin, Xu Wen Ng, Ying Ying Huang, Subbu S. Venkatraman, Jerry Harders, John C Burnett Jr, Horng H Chen. (2013). A Biodegradable in-situ Polymer Precipitation Delivery System for Sustained Delivery of a Novel Designer Natriuretic Peptide in an Experimental Model of Myocardial Infarction. ESC Congress 2013.
- Xu Wen Ng, Yingying Huang, Subbu S Venkatraman and Freddy Boey. (2013). Controlled release of novel cardiovascular peptides from biodegradable matrix. International Conference on Materials for Advance Technologies (ICMAT) 2013.
- Liu YC#, Peng Y#, Lwin NC, Wong TT, Venkatraman SS*, Mehta JS*. (2013). Optimization of subconjunctival biodegradable microfilms for sustained drug delivery to the anterior segment in a small animal model. Investigative Ophthalmology & Visual Science, 54(4), 2607-15.
- Soo Ghim Lim, Subbu S. Venkatraman, John C. Burnett Jr, Horng H. Chen. (2013). In-Vivo Evaluation of an In Situ Polymer Precipitation Delivery System for a Novel Natriuretic Peptide. PLoS ONE, 8(2).
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