Academic Profile

Academic Profile

Asst Prof Ali Gilles Tchenguise Miserez

Nanyang Assistant Professor (NRF)

School of Materials Science & Engineering
College of Engineering

Phone: (+65)63168979/65927947
Office: N4.1-01-16/RTP-XF-06

  • PhD (Matrls Sc & Eng) Ecole Polytechnique Federale de Lausanne 2003
  • MBA (Mgt of Tech) Ecole Polytechnique Federale de Lausanne 2002
  • MA (Matrls Sc & Eng) Ecole Polytechnique Federale de Lausanne 1998
Asst. Prof. Ali Miserez joined the School of Materials Science and Engineering in July 2009. He received his Master and Ph.D. degrees from the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland in 1998 and 2003, respectively, with specialization in Metallurgy, Advanced Composites Materials, and Fracture Mechanics. In 2004, Dr. Miserez was awarded a post-doctoral fellowship from the Swiss National Science Foundation to carry out research at the University of California, Santa Barbara (UCSB). At UCSB he expanded his research interests towards biomimetics, bio-inspired materials, and structure/biochemistry/properties relationships of hard and soft tissues. For his research on bio-inspired materials, he was awarded an advanced researcher fellowship from the Swiss NSF. As a research associate at UCSB, he was also supported by the National Institute of Health (NIH).

Dr. Miserez is especially interested in structural protein-based biological materials from the tissues of marine organisms. Such structures often feature unique combinations of biomechanical and physico-chemical characteristics, which can be exploited for designing novel materials in restorative applications or tissue engineering. Research in Dr. Miserez's lab has a strong multidisciplinary approach, encompassing mechanical behaviour of materials, wear and abrasion at the nano-scale, biochemistry of natural materials, and protein chemistry of structural proteins. We seek to discover and understand the fundamental biochemical, structural, and biosynthesis mechanisms of natural materials, with a long-term vision to mimick them to create novel, clean, and bio-inspired materials at a low energy cost.

Dr. Miserez's is the author or co-author of about 20 peer-reviewed publications published in well-respected journals in the fields of Materials Sciences such as "Acta Materiala", "Advanced Materials", or "Science". His recent work on the graded-mechanical and -biochemical properties of Cephalopod beaks was featured in numerous popular media such as National Geographic and BBC international.
Research Interests
Structural properties of biological materials from the macro-scale to the nano-scale
Abrasion and wear mechanisms of non-mineralized biocomposites and of biominerals
Elastomeric and structural properties of oviparous egg capsules materials
Protein chemistry of sclerotized hard-tissues from marine organisms, such as Cephalopod
Single-molecular force spectroscopy of structural and elastic proteins
Underwater adhesion mechanisms of adhesive proteins
Advanced Metal/Ceramic composites
Experimental Fracture Mechanics
Research Grant
  • Academic Research Fund Tier 2 (2012-2016)
  • NRF Competitive Research Program (2015-) [by National Research Foundation (NRF)]
  • NRF Research Fellowship (2011-)
  • Singapore Maritime Institute (2013-) [by Singapore Maritime Institute (SMI)]
Current Projects
  • Bio-Inspired Materials: Lessons from Biopolymeric Tissues of Marine Organisms
  • Biomimetic production of customizable bacterial cellulose through synthetic biology approach
  • Biomimetic-Based Antifouling Coatings as a Route to Imporve Energy Efficiency of Ships and Port Structures
  • Development of adhesive mimics for anti-fouling coatings and adhesion testing in the marine environment
  • Frontiers in Physical and Life Sciences: Bio-inspired and Biomimetic Materials (NRF-NRFRF2011-06)
  • Next-Gen Sequencing and Proteomics of Natural Biopolymers
  • Potential Marine Antifouling Agents : Synthesis and Formulation of Novel Halogeneatd Cyclopent - 2 - ones
  • Potential Marine Antifouling Agents: Synthesis and Formulation of Novel Halogenated Cyclopent-2-ones
  • Self-Assembly Mechanisms of 3D Protein-Based, Robust Marine Biopolymer
Selected Publications
  • Weaver JC, Wang Q, Miserez A,Tantuccio A, Stromberg R, Bozhilov, KN, Maxwell P, Nay R, Shinobu T, DiMasi H, Kisailus D. (2010). Analysis of an ultra hard magnetic biomineral in chiton radular teeth. Materials Today, 13(1-2), 42-52.
  • Miserez A., Wasko S.S., Carpenter C., Waite J.H. (2009). Non-Entropic and Reversible Long-Range Deformation of an Encapsulating Bioelastomer. Nature Materials, Accepted.
  • Miserez, A; Weaver, JC; Pedersen, PB; Schneeberk, T; Hanlon, RT; Kisailus, D; Birkedal, H. (2009). Microstructural and Biochemical Characterization of the Nanoporous Sucker Rings from Dosidicus gigas. Advanced Materials, 21(4), 401-406.
  • Miserez, A; Weaver, JC; Thurner, PJ; Aizenberg, J; Dauphin, Y; Fratzl, P; Morse, DE; Zok, FW. (2008). Effects of laminate architecture on fracture resistance of sponge biosilica: Lessons from nature. Advanced Functional Materials, 18(8), 1241-1248.
  • Miserez, A; Schneberk, T; Sun, CJ; Zok, FW; Waite, JH. (2008). The transition from stiff to compliant materials in squid beaks. Science, 319(5871), 1816-1819.

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