Academic Profile

Academic Profile

Prof Staffan Kjelleberg

Distinguished University Professor, School of Biological Sciences
Director

Email: laskjelleberg@ntu.edu.sg
Prof Staffan Kjelleberg

Biography
After completing his PhD, Staffan Kjelleberg conducted post-doctoral research at the University of New South Wales (UNSW), Australia before returning to Sweden to be a Research fellow with the Swedish Research Council (1983-1987). He was appointed Professor and Head of the Department of General and Marine Microbiology at the University of Göteborg in 1987. Kjelleberg was appointed Professor of Microbiology at UNSW in 1993, a position he continues to hold, and served as Head of the School of Microbiology and Immunology (1998-2000). He was appointed Visiting Professor at the Nanyang Technological University in 2008.
In 1994, Kjelleberg co-founded the Centre for Marine Bio-Innovation (CMB) at UNSW, where he currently serves as Director. The CMB is an international focal point for interdisciplinary research into biofilms and chemical signalling. Research at the CMB resulted in a strong patent portfolio for the development of quorum sensing blocking technology to combat bacterial biofilms and virulence. This technology was the basis for the start up company Biosignal Ltd, which was established in 1999, listed on ASX in 2004 and where he served as Research Director (2000-2005).
His professional experience also includes positions on national and international scientific societies, research councils, and governmental committees, advisory boards of biotechnology companies, editorial boards and editor of several scientific journals. He was President of the Swedish Society of Microbiology (1987-1992) and Vice President (2001-2004) and President (2004-2006) of the International Society for Microbial Ecology. He is currently Past President and member of the executive board of ISME (2006-2010). Kjelleberg regularly gives keynote presentations, invited lectures and serves as convenor at major scientific meetings. He is an elected fellow of the American Academy of Microbiology and was awarded the Scientia Professorship at UNSW in recognition of his scientific achievements.
Research Interests
Kjelleberg is internationally recognized for his studies of bacterial adaptive responses, signalling based communication between bacteria, bacterial biofilm biology, and chemically mediated interactions between bacteria and marine sessile organisms. His research approach includes molecular based studies of the mechanisms by which bacteria respond to prevailing conditions as well as environmental genomics of the biodiversity and function of natural microbial consortia. Kjelleberg has published more than 240 original papers in international refereed scientific journals and 30 books or book chapters. On the basis of strong collaborative research across microbiology, marine ecology and chemistry, and applied studies of the strategies employed by bacteria to build biofilms and communicate, substantial intellectual property has been established and utilized in biotechnology industries. Kjelleberg and his colleagues at the CMB also serve as a major research provider to several companies and organizations, including the Australian based Environmental Biotechnology Cooperative Research Centre.
Current Projects
  • A Novel Animal Model For The Treatment Of Chronic Poly-Microbial Infection Using Innovative Biofilm Patches
  • Biofilm Biology-Informed Biofilm Engineering
  • Cluster 3 - Microbial Biofilms
  • Development Of New Platforms And Molecules To Probe, Understand And Harness Microbial Biofilm Communities
  • Development of bio-chambers to support the reproducible growth of multiple-species biofilms
  • Haifa Project
  • Highly-conductive n-type organic wires for enhancing bioelectronic programme
  • Imaging and computation biology of mixed species biofilms
  • Mechanisms and Conduction Behaviour in Biofilms and Their Related Single Molecules
  • Next generation biofuels: improved butanol production titer by non-genetic means
  • Overcoming antibiotic resistance with lipid-polymer hybrid nanoparticle (LPN) delivery systems
  • Selective contact-active antimicrobial bio-macromolecules
  • The influence of gut microbiota composition (metagenome, metatranscriptome and metabolome) and its development/maturation on the development of eczema in Singaporean infacts and toddlers in the well-defined multi-ethnic GUSTO (Growing Up in Singapore Towards Healthy Outcomes) birth cohort
Selected Publications
  • Jingjing Guo, James C. S. Ho, Hokyun Chin, Alan E. Mark, Cheng Zhou, Staffan Kjelleberg, Bo Liedberg, Atul Parikh, Nam-Joon Cho, Jamie Hinks, Yuguang Mu, Thomas Seviour. (2019). Response of microbial membranes to butanol: interdigitation vs. disorder. Physical Chemistry Chemical Physics, .
  • jingjing guo, james c.s. ho, hokyun chin, alan e. mark, cheng zhou, staffan kjelleberg, bo liedberg, atul n. parikh, nam-joon cho, jamie, hinks, yuguang mu, thomas seviour. (2019). Response of microbial membranes to butanol: Q2 interdigitation vs. disorder. Physical Chemistry Chemical Physics, 10.1039/c9cp014.
  • Cheng Zhou, Geraldine W.N.Chia, James C.S. Ho, Alex S. Moreland, Thomas Seviour, Bo Liedberg, Atul N. Parikh, Staffan Kjelleberg, Jamie Hinks, Guillermo C. Bazan. (2019). A Chain-Elongated Oligophenylenevinylene Electrolyte Increases Microbial Membrane Stability. Advanced Materials, 31, 1808021.
  • Zhou C, Chia GWN, Ho JCS, Moreland AS, Seviour T, Parikh AN, Kjelleberg S, Hinks J, Bazan GC. (2019). A Chain‐Elongated Oligophenylenevinylene Electrolyte Increases Microbial Membrane Stability. Advanced Materials, .
  • Seviour T, Derlon N, Dueholm MS, Flemming HC, Girbal-Neuhauser E, Horn H, Kjelleberg S, van Loosdrecht MCM, Lotti T, Malpei MF, Nerenberg R, Neu TR, Paul E, Yu H, Lin Y. (2019). Extracellular polymeric substances of biofilms: suffering from an identity crisis. Water Research, 151, 1-7.

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